Symptoms of advanced esophageal cancer are as follows: 1. difficulty in swallowing: persistent and progressively worsening difficulty in swallowing; 2. food reflux: refluxed material containing undigested food, mucus, sometimes accompanied by blood, pus and blood; 3. pain in swallowing: pain when swallowing; 4. weight loss, advanced cachexia; 5. other: hoarseness due to tumour compression of the recurrent laryngeal nerve; eruption and phrenic nerve paralysis due to tumour invasion of the phrenic nerve; shortness of breath, shortness of breath and dry cough due to tumour compression of the oesophagus; haemorrhage due to tumour invasion of the aorta; oesophageal tracheal fistula due to oesophageal cancer connecting with the trachea, resulting in difficulty in breathing, coughing and coughing up blood.